TREATMENT READING
Langerhans Cell Histiocytosis
Choose a source section by treatment, subtype or setting. Patient and professional reading are labelled separately.
Selected text from the National Cancer Institute, with original links and dates. This Triangle reading page is not an NCI PDQ summary. Source topics may be broader than an individual diagnosis.
5 studies cited in this topic · see design and results →
Explore 2 related disease and treatment settings → · Source-derived catalogue; clinical review pending.
Certain factors affect prognosis (chance of recovery) and treatment options.
Treatment of LCH is based on where LCH cells are found in the body and whether the LCH is low risk or high risk.
Sometimes LCH continues to grow or comes back after treatment.
Treatment Option Overview for LCH
Key Points
There are different types of treatment for patients with Langerhans cell histiocytosis (LCH).
Children with LCH should have their treatment planned by a team of health care providers who are experts in treating childhood cancer or LCH.
Nine types of standard treatment are used to treat LCH.
Chemotherapy
Surgery
Radiation therapy
Photodynamic therapy
Immunotherapy
Targeted therapy
Other drug therapy
Stem cell transplant
Observation
New types of treatment are being tested in clinical trials.
Treatment for Langerhans cell histiocytosis may cause side effects.
Patients may want to think about taking part in a clinical trial.
Patients can enter clinical trials before, during, or after starting their treatment.
Follow-up tests may be needed.
Treatment of Low-Risk LCH in Children
Skin Lesions
Lesions in Bones or Other Low-Risk Organs
CNS Lesions
Treatment of High-Risk LCH in Children
Treatment of Progressive, Refractory, or Recurrent Childhood LCH in Children
Treatment of LCH in Adults
Lung Lesions
Bone Lesions
Skin Lesions
Single-System and Multisystem Disease
Preserved source evidence · Independent clinical review pending · Not medical advice
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