TriangleFOR PATIENTS · SOURCE READING
Skin Lesions
Source: Langerhans Cell Histiocytosis Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: June 6, 2024 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Context: Treatment of LCH in Adults
Treatment for LCH that affects only the skin in adults may include:
Source links and citations
Surgery.
Source links and citations
Steroid or other drug therapy (tacrolimus or imiquimod) applied or injected into the skin.
Source links and citations
Photodynamic therapy with psoralen and ultraviolet A (PUVA) radiation.
Source links and citations
UVB radiation therapy.
Source links and citations
Chemotherapy or immunotherapy given by mouth, such as methotrexate, thalidomide, or hydroxyurea.
Source links and citations
Treatment for LCH that affects the skin and other body systems in adults may include:
Chemotherapy.
Preserved source evidence · Independent clinical review pending · Not medical advice