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Malignant testicular GCTs in postpubertal males

Source: Childhood Extracranial Germ Cell Tumors Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: November 5, 2024 · Captured 2026-09-09.

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Context: Treatment of Malignant Gonadal GCTs in Children / Childhood Malignant Testicular GCTs

The treatment options described for prepubertal males may not be strictly applicable to postpubertal males. In particular, retroperitoneal lymph node dissection is a treatment option and may play a crucial role [16] in the initial treatment of patients or in subsequent treatment of patients with residual disease after chemotherapy for metastatic testicular GCT.[17,18] A meta-analysis showed that patients older than 11 years were at higher risk of recurrence.[8] The number of males aged 11 to 15 years with GCT is small; it is possible that these patients should be treated according to adult standards. For more information about the treatment of malignant testicular GCTs in postpubertal males, see Testicular Cancer Treatment.

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