FOR PATIENTS · SOURCE READING
High-dose chemotherapy with stem cell transplant
Source: Childhood Extracranial Germ Cell Tumors Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: July 19, 2024 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Context: Treatment Option Overview / New types of treatment are being tested in clinical trials.
High doses of chemotherapy are given to kill cancer cells. Healthy cells, including blood-forming cells, are also destroyed by the cancer treatment. Stem cell transplant is a treatment to replace the blood-forming cells. Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored. After the patient completes chemotherapy, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the body's blood cells.
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Preserved source evidence · Independent clinical review pending · Not medical advice
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