HEALTH PROFESSIONAL · SOURCE READING
Treatment of Localized Ewing Sarcoma
Source: Ewing Sarcoma and Undifferentiated Small Round Cell Sarcomas of Bone and Soft Tissue Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: November 27, 2024 · Captured 2026-09-09.
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Standard treatment options for localized Ewing sarcoma include the following:
Chemotherapy.
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Local-control measures:
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High-dose chemotherapy with autologous stem cell rescue.
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Because most patients with apparently localized disease at diagnosis have occult metastatic disease, multidrug chemotherapy and surgery and/or radiation therapy (to control local disease) is indicated in the treatment of all patients.[1-8] Patients with localized Ewing sarcoma who receive current treatment regimens achieve event-free survival (EFS) and overall survival (OS) rates of approximately 70% at 5 years after diagnosis.[9]
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