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← Ewing Sarcoma and Undifferentiated Small Round Cell Sarcomas of Bone and Soft Tissue

HEALTH PROFESSIONAL · SOURCE READING

Treatment of Localized Ewing Sarcoma

Source: Ewing Sarcoma and Undifferentiated Small Round Cell Sarcomas of Bone and Soft Tissue Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: November 27, 2024 · Captured 2026-09-09.

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Standard treatment options for localized Ewing sarcoma include the following:

Chemotherapy.

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Local-control measures:

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Local-control measures:

Surgery.

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Local-control measures:

Radiation therapy.

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High-dose chemotherapy with autologous stem cell rescue.

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Because most patients with apparently localized disease at diagnosis have occult metastatic disease, multidrug chemotherapy and surgery and/or radiation therapy (to control local disease) is indicated in the treatment of all patients.[1-8] Patients with localized Ewing sarcoma who receive current treatment regimens achieve event-free survival (EFS) and overall survival (OS) rates of approximately 70% at 5 years after diagnosis.[9]

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Preserved source evidence · Not medical advice