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HEALTH PROFESSIONAL · SOURCE READING

External-beam radiation therapy (EBRT) with or without concomitant chemotherapy

Source: Bladder Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 2, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Stage IV Bladder Cancer / Treatment Options for Stage IV Bladder Cancer / Treatment options for patients with T4b, N0, M0 disease

Definitive radiation therapy with or without concurrent chemotherapy, evaluated mainly in patients with locally advanced (T2–T4) disease, appears to have minimal curative potential in patients with regional lymph node metastases.[34,35] Patients with evidence of lymph node metastases have generally been excluded from phase III trials of radiation therapy.[36,37]

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