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NCT03109262 · OUTCOME

Image Quality for 90-Y PET/CT Scans

Yttrium-90 (Y90) Glass Microspheres PET/CT in Imaging Patients With Liver Tumors · Source last updated 2022-01-10

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEAN
Unit
units on a scale
Interval / dispersion
Standard Deviation
Time frame
1 day

What was measured

Image quality for 90Y PET/CT scan images was assessed relative to the expected image quality of Standard of Care (SoC) 99mTc-MAA SPECT/CT scans obtained from the same participant. Assessments were conducted at 5, 10, 15 and 20 minutes after infusion. Scans were assessed on a 1 to 5 Likert scale by 2 Nuclear Medicine physicians who were blinded to patient information. The Likert scale for image quality was established as follows: 1. = Non-diagnostic 2. = Suboptimal 3. = Acceptable 4. = Good 5. = Excellent, equivalent to a SoC 99mTc-MAA SPECT/CT scan The scans for each individual participant at each timepoint was scored on the Likert scale, as determined by the 2 Nuclear Medicine physicians. The outcome is reported as the overall mean of the physician determinations for each time point, with standard deviation.

Groups in this outcome

Yttrium Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans

All participants receive both Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans * Computed Tomography (CT): As part of PET/CT and SPECT/CT scans. * Positron Emission Tomography (PET): As part of PET/CT scan * Single-photon emission computerized tomography (SPECT) scan: As part of SPECT/CT scan * 90-Yttrium (Y-90) Glass Microspheres: Radiolabel for PET/CT scan * Technetium 99mTc albumin aggregated (99mTc-MAA): Radiolabel for 99mTc-MAA SPECT/CT Scan

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Yttrium Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans42

Reported measurements

5 minutes
Values in units on a scale · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Yttrium Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans3.560.43Not reportedNot reportedNot reported
10 minutes
Values in units on a scale · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Yttrium Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans4.630.49Not reportedNot reportedNot reported
15 minutes
Values in units on a scale · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Yttrium Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans4.890.28Not reportedNot reportedNot reported
20 minutes
Values in units on a scale · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Yttrium Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans4.930.21Not reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        spread
        0.43
        value
        3.56
    title
    5 minutes
  2. categories
    1. measurements
      1. group Id
        OG000
        spread
        0.49
        value
        4.63
    title
    10 minutes
  3. categories
    1. measurements
      1. group Id
        OG000
        spread
        0.28
        value
        4.89
    title
    15 minutes
  4. categories
    1. measurements
      1. group Id
        OG000
        spread
        0.21
        value
        4.93
    title
    20 minutes
denoms
  1. counts
    1. group Id
      OG000
      value
      42
    units
    Participants
description
Image quality for 90Y PET/CT scan images was assessed relative to the expected image quality of Standard of Care (SoC) 99mTc-MAA SPECT/CT scans obtained from the same participant. Assessments were conducted at 5, 10, 15 and 20 minutes after infusion. Scans were assessed on a 1 to 5 Likert scale by 2 Nuclear Medicine physicians who were blinded to patient information. The Likert scale for image quality was established as follows: 1. = Non-diagnostic 2. = Suboptimal 3. = Acceptable 4. = Good 5. = Excellent, equivalent to a SoC 99mTc-MAA SPECT/CT scan The scans for each individual participant at each timepoint was scored on the Likert scale, as determined by the 2 Nuclear Medicine physicians. The outcome is reported as the overall mean of the physician determinations for each time point, with standard deviation.
dispersion Type
Standard Deviation
groups
  1. description
    All participants receive both Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans * Computed Tomography (CT): As part of PET/CT and SPECT/CT scans. * Positron Emission Tomography (PET): As part of PET/CT scan * Single-photon emission computerized tomography (SPECT) scan: As part of SPECT/CT scan * 90-Yttrium (Y-90) Glass Microspheres: Radiolabel for PET/CT scan * Technetium 99mTc albumin aggregated (99mTc-MAA): Radiolabel for 99mTc-MAA SPECT/CT Scan
    id
    OG000
    title
    Yttrium Y-90 PET/CT vs 99mTc-MAA SPECT/CT Scans
param Type
MEAN
reporting Status
POSTED
time Frame
1 day
title
Image Quality for 90-Y PET/CT Scans
type
PRIMARY
unit Of Measure
units on a scale

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice