Participant flow

A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2) · Source last updated 2023-06-12

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups

1. description

   Patients with a deleterious BRCA (breast cancer susceptibility gene) mutation detected in their tumor. Part 1 enrolled patients who received ≥ 1 prior platinum-based regimen and had platinum-sensitive disease.

   id

   FG000

   title

   Part 1: tBRCA

2. description

   Patients without a BRCA mutation in their tumor, but have high LOH (loss of heterozygosity). Part 1 enrolled patients received ≥ 1 prior platinum-based regimen and had platinum-sensitive disease.

   id

   FG001

   title

   Part 1: Non-tBRCA LOH+

3. description

   Patients without a BRCA mutation in their tumor, but have low LOH. Part 1 enrolled patients received ≥ 1 prior platinum-based regimen and had platinum-sensitive disease.

   id

   FG002

   title

   Part 1: Non-tBRCA LOH-

4. description

   Patients without a BRCA mutation in their tumor, and have unknown LOH due to missing results and/or failed test result(s). Part 1 enrolled patients received ≥ 1 prior platinum-based regimen and had platinum-sensitive disease.

   id

   FG003

   title

   Part 1: Non-tBRCA LOH Unknown

5. description

   Patients with a deleterious BRCA mutation detected in their tumor. Part 2 enrolled patients who received at least 3, but no more than 4, prior chemotherapy regimens.

   id

   FG004

   title

   Part 2: tBRCA

6. description

   Patients without a BRCA mutation in their tumor, but have high LOH. Part 2 enrolled patients who received at least 3, but no more than 4, prior chemotherapy regimens.

   id

   FG005

   title

   Part 2: Non-tBRCA LOH+

7. description

   Patients without a BRCA mutation in their tumor, but have low LOH. Part 2 enrolled patients who received at least 3, but no more than 4, prior chemotherapy regimens.

   id

   FG006

   title

   Part 2: Non-tBRCA LOH-

8. description

   Patients without a BRCA mutation in their tumor, and have unknown LOH due to missing results and/or failed test result(s). Part 2 enrolled patients who received at least 3, but no more than 4, prior chemotherapy regimens.

   id

   FG007

   title

   Part 2: Non-tBRCA LOH Unknown

periods

1. drop Withdraws

   1. reasons

      1. group Id

         FG000

         num Subjects

         6

      2. group Id

         FG001

         num Subjects

         2

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         1

      5. group Id

         FG004

         num Subjects

         4

      6. group Id

         FG005

         num Subjects

         1

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      type

      Ongoing

   milestones

   1. achievements

      1. group Id

         FG000

         num Subjects

         40

      2. group Id

         FG001

         num Subjects

         82

      3. group Id

         FG002

         num Subjects

         70

      4. group Id

         FG003

         num Subjects

         12

      5. group Id

         FG004

         num Subjects

         84

      6. group Id

         FG005

         num Subjects

         73

      7. group Id

         FG006

         num Subjects

         107

      8. group Id

         FG007

         num Subjects

         23

      type

      STARTED

   2. achievements

      1. group Id

         FG000

         num Subjects

         34

      2. group Id

         FG001

         num Subjects

         80

      3. group Id

         FG002

         num Subjects

         70

      4. group Id

         FG003

         num Subjects

         11

      5. group Id

         FG004

         num Subjects

         80

      6. group Id

         FG005

         num Subjects

         72

      7. group Id

         FG006

         num Subjects

         107

      8. group Id

         FG007

         num Subjects

         23

      type

      COMPLETED

   3. achievements

      1. group Id

         FG000

         num Subjects

         6

      2. group Id

         FG001

         num Subjects

         2

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         1

      5. group Id

         FG004

         num Subjects

         4

      6. group Id

         FG005

         num Subjects

         1

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      type

      NOT COMPLETED

   title

   Overall Study

recruitment Details

491 subjects were recruited from 64 sites across 6 countries.

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice