TriangleNCT00667342 · OUTCOME
P95 of Ktrans by Good and Poor Response
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEAN
- Unit
- min(-1)
- Interval / dispersion
- Standard Error
- Time frame
- at week 10 after start of therapy
What was measured
The response is based on the Huvos grade of histologic response for DCE-MRI comparisons and is defined as good for ≥90% necrosis and poor for less than 90%. P95 denotes the level of each kinetic parameter exceeding 95% of its values in each tumor.
Analysis population: Two Stratum A participants with no histologic response were excluded.
Groups in this outcome
All Participants
All 42 evaluable participants in this study had osteosarcoma. This analysis includes 29 Stratum A participants who had primary tumors potentially resectable by aggressive surgery, such as limb-salvage surgery or amputation, and no evidence of metastasis, and 11 Stratum C participants who had metastatic tumors.
| Group | Source count |
|---|---|
| All Participants | 40 |
Reported measurements
Poor Response
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| All Participants | 0.2047 | 0.0224 | Not reported | Not reported | Not reported |
Good Response
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| All Participants | 0.1228 | 0.0136 | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- spread
- 0.0224
- value
- 0.2047
- title
- Poor Response
- categories
- measurements
- group Id
- OG000
- spread
- 0.0136
- value
- 0.1228
- title
- Good Response
- denoms
- counts
- group Id
- OG000
- value
- 40
- units
- Participants
- description
- The response is based on the Huvos grade of histologic response for DCE-MRI comparisons and is defined as good for ≥90% necrosis and poor for less than 90%. P95 denotes the level of each kinetic parameter exceeding 95% of its values in each tumor.
- dispersion Type
- Standard Error
- groups
- description
- All 42 evaluable participants in this study had osteosarcoma. This analysis includes 29 Stratum A participants who had primary tumors potentially resectable by aggressive surgery, such as limb-salvage surgery or amputation, and no evidence of metastasis, and 11 Stratum C participants who had metastatic tumors.
- id
- OG000
- title
- All Participants
- param Type
- MEAN
- population Description
- Two Stratum A participants with no histologic response were excluded.
- reporting Status
- POSTED
- time Frame
- at week 10 after start of therapy
- title
- P95 of Ktrans by Good and Poor Response
- type
- SECONDARY
- unit Of Measure
- min(-1)
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice