{"classes":[{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.0224","value":"0.2047"}]}],"title":"Poor Response"},{"categories":[{"measurements":[{"groupId":"OG000","spread":"0.0136","value":"0.1228"}]}],"title":"Good Response"}],"denoms":[{"counts":[{"groupId":"OG000","value":"40"}],"units":"Participants"}],"description":"The response is based on the Huvos grade of histologic response for DCE-MRI comparisons and is defined as good for ≥90% necrosis and poor for less than 90%. P95 denotes the level of each kinetic parameter exceeding 95% of its values in each tumor.","dispersionType":"Standard Error","groups":[{"description":"All 42 evaluable participants in this study had osteosarcoma. This analysis includes 29 Stratum A participants who had primary tumors potentially resectable by aggressive surgery, such as limb-salvage surgery or amputation, and no evidence of metastasis, and 11 Stratum C participants who had metastatic tumors.","id":"OG000","title":"All Participants"}],"paramType":"MEAN","populationDescription":"Two Stratum A participants with no histologic response were excluded.","reportingStatus":"POSTED","timeFrame":"at week 10 after start of therapy","title":"P95 of Ktrans by Good and Poor Response","type":"SECONDARY","unitOfMeasure":"min(-1)"}