TriangleNCT03805971 · STUDY IN CONTEXT
Probe Based Confocal Laser Endomicroscopy During Thoracoscopy for Pleural Malignancies Diagnosis.
Draft scope assessment: narrower. Linked by condition-string match at the cancer-entity level. The study's eligibility - stage, biomarker, treatment line and prior therapy - has not been reconciled against this page's definition, so its population is narrower than this page in ways not yet recorded. The condition was transformed or resolved through the terminology hierarchy to reach this cancer type, so the link itself is a candidate a reviewer must confirm. Found by searching ClinicalTrials.gov for this cancer type, restricted to studies that have posted results to the registry. No FDA notice, FDA label or NCI summary held by this site cites this study. Because the search asked for posted results, studies without posted results were never looked for, so their absence from this page means nothing.
Read the full study record and all posted results →
Linked outcomes
Eleven preselected criteria were assessed in their ability to distinguish benign from malignant pleura Qualitative variables are presented in this table
Eleven preselected pCLE criteria were assessed in their ability to distinguish benign from malignant pleura. Here are presented Mean cell size and maximum vascular diameter
Eleven preselected pCLE criteria were assessed in their ability to distinguish benign from malignant pleura. Quantitative criteria are presented in this table. Here is presented the mean cellular density
Eleven preselected pCLE criteria were assessed in their ability to distinguish benign from malignant pleura. Quantitative criteria are presented in this table. Here is presented the vascular density.
The investigators performing the thoracoscopy had to score the pCLE acquisition. Three level of quality were used: Good, Acceptable, Low.
Reported safety
Quality of life and patient-reported measures
No linked quality-of-life measure is recorded for this setting and study.
Full draft applicability and source-link record
- trial
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- trial label
- Probe Based Confocal Laser Endomicroscopy During Thoracoscopy for Pleural Malignancies Diagnosis.
- applicability
- narrower
- applicability note
- Linked by condition-string match at the cancer-entity level. The study's eligibility - stage, biomarker, treatment line and prior therapy - has not been reconciled against this page's definition, so its population is narrower than this page in ways not yet recorded. The condition was transformed or resolved through the terminology hierarchy to reach this cancer type, so the link itself is a candidate a reviewer must confirm.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- provenance class
- registry-condition-search
- discovery note
- Found by searching ClinicalTrials.gov for this cancer type, restricted to studies that have posted results to the registry. No FDA notice, FDA label or NCI summary held by this site cites this study. Because the search asked for posted results, studies without posted results were never looked for, so their absence from this page means nothing.
- outcome Count
- 5
- harms Count
- 1
- qol Count
- 0
- outcomes
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0000
- source section id
- NCT03805971-om-0000
- source outcome index
- 0
- endpoint
- Pleural Carcinomatosis Identification (Compared to Standard Biopsies). Qualitative Criteria.
- endpoint definition
- Eleven preselected criteria were assessed in their ability to distinguish benign from malignant pleura Qualitative variables are presented in this table
- time origin
- One day.
- analysis role
- primary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0001
- source section id
- NCT03805971-om-0001
- source outcome index
- 1
- endpoint
- Pleural Carcinomatosis Identification (Compared to Standard Biopsies), Quantitative Criteria.
- endpoint definition
- Eleven preselected pCLE criteria were assessed in their ability to distinguish benign from malignant pleura. Here are presented Mean cell size and maximum vascular diameter
- time origin
- One day
- analysis role
- primary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Some criteria were not assessable for some patients.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0003
- source section id
- NCT03805971-om-0003
- source outcome index
- 3
- endpoint
- Pleural Carcinomatosis Identification (Compared to Standard Biopsies), Quantitative Criteria.
- endpoint definition
- Eleven preselected pCLE criteria were assessed in their ability to distinguish benign from malignant pleura. Quantitative criteria are presented in this table. Here is presented the mean cellular density
- time origin
- One day
- analysis role
- primary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Some criteria were not assessable for some patients.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0004
- source section id
- NCT03805971-om-0004
- source outcome index
- 4
- endpoint
- Pleural Carcinomatosis Identification (Compared to Standard Biopsies), Quantitative Criteria.
- endpoint definition
- Eleven preselected pCLE criteria were assessed in their ability to distinguish benign from malignant pleura. Quantitative criteria are presented in this table. Here is presented the vascular density.
- time origin
- One day
- analysis role
- primary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Some criteria were not assessable for some patients.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0002
- source section id
- NCT03805971-om-0002
- source outcome index
- 2
- endpoint
- Quality of the pCLE Acquisition
- endpoint definition
- The investigators performing the thoracoscopy had to score the pCLE acquisition. Three level of quality were used: Good, Acceptable, Low.
- time origin
- One day
- analysis role
- secondary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- arms
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0000
- arm key
- OG000
- arm label
- Benign Pleura
- regimen
- Participants with a benign pleura histological diagnosis.
- analyzed count
- 36
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0000#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0000
- arm key
- OG001
- arm label
- Malignant Pleural Infiltrations
- regimen
- Participants with a malignant pleural disease demonstrated by biopsies.
- analyzed count
- 26
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0000#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0001
- arm key
- OG000
- arm label
- Benign Pleura
- regimen
- Participants with a benign pleura histological diagnosis.
- analyzed count
- 36
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0001#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0001
- arm key
- OG001
- arm label
- Malignant Pleural Infiltrations
- regimen
- Participants with a malignant pleural disease demonstrated by biopsies.
- analyzed count
- 26
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0001#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0002
- arm key
- OG000
- arm label
- Benign Pleura
- regimen
- Participants with a benign pleura histological diagnosis.
- analyzed count
- 36
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0002#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0002
- arm key
- OG001
- arm label
- Malignant Pleural Infiltrations
- regimen
- Participants with a malignant pleural disease demonstrated by biopsies.
- analyzed count
- 26
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0002#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0003
- arm key
- OG000
- arm label
- Benign Pleura
- regimen
- Participants with a benign pleura histological diagnosis.
- analyzed count
- 36
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0003#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0003
- arm key
- OG001
- arm label
- Malignant Pleural Infiltrations
- regimen
- Participants with a malignant pleural disease demonstrated by biopsies.
- analyzed count
- 26
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0003#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0004
- arm key
- OG000
- arm label
- Benign Pleura
- regimen
- Participants with a benign pleura histological diagnosis.
- analyzed count
- 36
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0004#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- outcome key
- om-0004
- arm key
- OG001
- arm label
- Malignant Pleural Infiltrations
- regimen
- Participants with a malignant pleural disease demonstrated by biopsies.
- analyzed count
- 26
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03805971-om-0004#groups/OG001
- harms
- release id
- clinical-indications-draft-1
- disease state id
- ds-thoracic-neoplasm
- nct id
- NCT03805971
- harm key
- EG000
- source section id
- NCT03805971-ae
- event group key
- EG000
- event group label
- Patient Aged More Than 18 Years Admitted for Thoracoscopy
- serious affected
- 0
- serious at risk
- 62
- other affected
- 0
- other at risk
- 62
- frequency threshold
- 1
- collection period
- 1 day
- event definition
- Source null
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- quality of life
- setting source links
Preserved source evidence · Not medical advice