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DISEASE & TREATMENT SETTING

Osteosarcoma

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Osteosarcoma

Source population
Not part of this definition
Disease extent
Not part of this definition
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      unresolved
      derivation note
      Derived from NCI topic(s): Osteosarcoma and Undifferentiated Pleomorphic Sarcoma of Bone. Strongest NCIt resolution: ambiguous. Entity-level scope; stage, biomarker and treatment line are not yet part of this definition.
      source wording
      Source null
      3 more-specific settings

      Study evidence for this setting

      13 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00520936 · Source cited / selected · Scope: narrower

      A Study of Pemetrexed in Children With Recurrent Cancer

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00667342 · Registry condition search · Scope: narrower

      A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00831844 · Registry condition search · Scope: narrower

      Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

      1 outcome links · 10 safety-group records · 0 quality-of-life measures

      →

      NCT01154452 · Registry condition search · Scope: narrower

      Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

      3 outcome links · 4 safety-group records · 0 quality-of-life measures

      →

      NCT01553539 · Registry condition search · Scope: narrower

      Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery

      5 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT02048371 · Source cited / selected · Scope: narrower

      SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes

      6 outcome links · 8 safety-group records · 0 quality-of-life measures

      →

      NCT02162732 · Registry condition search · Scope: narrower

      Molecular-Guided Therapy for Childhood Cancer

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02432274 · Source cited / selected · Scope: narrower

      Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma

      6 outcome links · 9 safety-group records · 1 quality-of-life measures

      →

      NCT03213665 · Source cited / selected · Scope: narrower

      Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A

      5 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT03213678 · Registry condition search · Scope: narrower

      Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATC

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT03213704 · Registry condition search · Scope: narrower

      Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment

      5 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT03698994 · Registry condition search · Scope: narrower

      Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT04154189 · Source cited / selected · Scope: narrower

      A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcom

      6 outcome links · 3 safety-group records · 2 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
      1. release id
        clinical-indications-draft-1
        disease state id
        ds-osteosarcoma
        binding id
        ncit-C6585
        source collection
        ncit-concept
        source key
        C6585
        source excerpt
        Source null
        match status
        ambiguous
        match note
        Resolution status: ambiguous.
        recorded at
        2026-09-10T00:00:00Z
      2. release id
        clinical-indications-draft-1
        disease state id
        ds-osteosarcoma
        binding id
        ncit-C9145
        source collection
        ncit-concept
        source key
        C9145
        source excerpt
        Source null
        match status
        ambiguous
        match note
        Resolution status: ambiguous.
        recorded at
        2026-09-10T00:00:00Z
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice