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DISEASE & TREATMENT SETTING

locally advanced Non-Small Cell Lung Cancer

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Locally advanced unresectable tumors

Broader topic: Non-Small Cell Lung Cancer

Source population
Not part of this definition
Disease extent
locally-advanced
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
unresectable
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from an NCI treatment-summary heading. NCI PDQ is an evidence summary, not a practice guideline, and only the dimensions the heading states are part of this definition.
      source wording
      Locally advanced unresectable tumors

      Study evidence for this setting

      93 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00101413 · Source cited / selected · Scope: unclear

      BAY43-9006 - Phase II Study in Non-Small Cell Lung Carcinoma (NSCLC)

      5 outcome links · 1 safety-group records · 1 quality-of-life measures

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      NCT00102804 · Source cited / selected · Scope: unclear

      Pemetrexed and Best Supportive Care Versus Placebo and Best Supportive Care in Non-Small Cell Lung Cancer (NSCLC)

      6 outcome links · 2 safety-group records · 2 quality-of-life measures

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      NCT00423150 · Registry condition search · Scope: unclear

      Phase 2 Study of Temozolomide in Pre-Selected Advanced Aerodigestive Tract Cancers (Study P04273AM2)(TERMINATED)

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

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      NCT00446225 · Source cited / selected · Scope: unclear

      Phase III Study (Tarceva®) vs Chemotherapy to Treat Advanced Non-Small Cell Lung Cancer in Patients With Mutations in the TK Domain of EGFR

      4 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00556322 · Source cited / selected · Scope: unclear

      A Study of Tarceva (Erlotinib) and Standard of Care Chemotherapy in Patients With Advanced, Recurrent, or Metastatic Non-Small Cell Lung Cancer (NSCLC)

      6 outcome links · 2 safety-group records · 10 quality-of-life measures

      →

      NCT00585195 · Source cited / selected · Scope: unclear

      A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer

      6 outcome links · 21 safety-group records · 0 quality-of-life measures

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      NCT00686959 · Source cited / selected · Scope: unclear

      Chemotherapy and Radiation in Treating Participants With Stage 3 Non-Small Cell Lung Cancer

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

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      NCT00789373 · Source cited / selected · Scope: unclear

      A Study of Induction and Maintenance Treatment of Advanced Non-squamous Non-Small Cell Lung Cancer

      6 outcome links · 3 safety-group records · 2 quality-of-life measures

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      NCT00819169 · Registry condition search · Scope: unclear

      QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors

      6 outcome links · 9 safety-group records · 0 quality-of-life measures

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      NCT00923481 · Registry condition search · Scope: unclear

      A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and R

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

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      NCT00932893 · Source cited / selected · Scope: unclear

      An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anapla

      6 outcome links · 2 safety-group records · 5 quality-of-life measures

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      NCT01177397 · Registry condition search · Scope: unclear

      Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma

      6 outcome links · 12 safety-group records · 0 quality-of-life measures

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      NCT01327612 · Registry condition search · Scope: unclear

      Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

      6 outcome links · 7 safety-group records · 0 quality-of-life measures

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      NCT01390818 · Registry condition search · Scope: unclear

      Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors

      6 outcome links · 15 safety-group records · 0 quality-of-life measures

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      NCT01401907 · Registry condition search · Scope: unclear

      Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies

      6 outcome links · 2 safety-group records · 3 quality-of-life measures

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      NCT01451632 · Registry condition search · Scope: unclear

      A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

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      NCT01457417 · Registry condition search · Scope: unclear

      A Study of DKN-01 in Multiple Myeloma or Advanced Solid Tumors

      6 outcome links · 5 safety-group records · 0 quality-of-life measures

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      NCT01507428 · Source cited / selected · Scope: unclear

      Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy for Stage III Non-small Cell Lung Cancer

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

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      NCT01523587 · Source cited / selected · Scope: unclear

      LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy

      6 outcome links · 2 safety-group records · 3 quality-of-life measures

      →

      NCT01625234 · Source cited / selected · Scope: unclear

      Phase 1/2 Study of X-396, an Oral ALK Inhibitor, in Patients With ALK-positive Non-Small Cell Lung Cancer

      6 outcome links · 7 safety-group records · 0 quality-of-life measures

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      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice