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DISEASE & TREATMENT SETTING

BEIZRAY: metastatic Non-small cell lung cancer after prior therapy

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1.2 Non-small Cell Lung Cancer BEIZRAY as a single agent is indicated for the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of prior platinum-based chemotherapy.

Broader topic: Non-Small Cell Lung Cancer

Source population
Not part of this definition
Disease extent
metastatic
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
    1. class
      after failure of prior platinum-based chemotherapy
      status
      required
    derivation status
    source-attested
    derivation note
    Scoped from the FDA approved indication for BEIZRAY (product label). Only dimensions stated in that wording are part of this definition.
    source wording
    1.2 Non-small Cell Lung Cancer BEIZRAY as a single agent is indicated for the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of prior platinum-based chemotherapy.

    Study evidence for this setting

    76 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

    NCT00556322 · Source cited / selected · Scope: unclear

    A Study of Tarceva (Erlotinib) and Standard of Care Chemotherapy in Patients With Advanced, Recurrent, or Metastatic Non-Small Cell Lung Cancer (NSCLC)

    6 outcome links · 2 safety-group records · 10 quality-of-life measures

    →

    NCT00819169 · Registry condition search · Scope: unclear

    QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors

    6 outcome links · 9 safety-group records · 0 quality-of-life measures

    →

    NCT00896454 · Source cited / selected · Scope: unclear

    Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT00981058 · Source cited / selected · Scope: unclear

    First-line Treatment of Participants With Stage IV Squamous Non-Small Cell Lung Cancer With Necitumumab and Gemcitabine-Cisplatin

    6 outcome links · 2 safety-group records · 3 quality-of-life measures

    →

    NCT00982111 · Source cited / selected · Scope: unclear

    First-line Treatment of Patients With Stage IV Nonsquamous Non-Small Cell Lung Cancer With Necitumumab (IMC-11F8) and Pemetrexed-Cisplatin

    6 outcome links · 2 safety-group records · 3 quality-of-life measures

    →

    NCT01139775 · Registry condition search · Scope: unclear

    A Study in Non Small Cell Lung Cancer

    6 outcome links · 3 safety-group records · 1 quality-of-life measures

    →

    NCT01168973 · Source cited / selected · Scope: unclear

    A Study of Chemotherapy and Ramucirumab Versus Chemotherapy Alone in Second Line Non-Small Cell Lung Cancer (NSCLC) Participants Who Received Prior First Line Platinum-based Chemot

    6 outcome links · 2 safety-group records · 2 quality-of-life measures

    →

    NCT01327612 · Registry condition search · Scope: unclear

    Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

    6 outcome links · 7 safety-group records · 0 quality-of-life measures

    →

    NCT01390818 · Registry condition search · Scope: unclear

    Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors

    6 outcome links · 15 safety-group records · 0 quality-of-life measures

    →

    NCT01631552 · Source cited / selected · Scope: unclear

    Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer

    6 outcome links · 1 safety-group records · 0 quality-of-life measures

    →

    NCT01642004 · Source cited / selected · Scope: unclear

    Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Advanced or Metastatic Squamous Cell Non-small Cell Lung Cancer (NSCLC) (CheckMate 017)

    6 outcome links · 5 safety-group records · 1 quality-of-life measures

    →

    NCT01673867 · Source cited / selected · Scope: unclear

    Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Metastatic Non-squamous NSCLC

    6 outcome links · 5 safety-group records · 1 quality-of-life measures

    →

    NCT01761240 · Registry condition search · Scope: unclear

    Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC

    6 outcome links · 5 safety-group records · 0 quality-of-life measures

    →

    NCT01774721 · Source cited / selected · Scope: unclear

    ARCHER1050: A Study of Dacomitinib vs. Gefitinib in 1st-Line Treatment Of Advanced NSCLC.

    6 outcome links · 3 safety-group records · 2 quality-of-life measures

    →

    NCT01806675 · Registry condition search · Scope: unclear

    18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

    5 outcome links · 3 safety-group records · 1 quality-of-life measures

    →

    NCT01903993 · Source cited / selected · Scope: unclear

    A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

    6 outcome links · 2 safety-group records · 0 quality-of-life measures

    →

    NCT02008227 · Source cited / selected · Scope: unclear

    A Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing Therapy

    6 outcome links · 2 safety-group records · 15 quality-of-life measures

    →

    NCT02014116 · Registry condition search · Scope: unclear

    A Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their Body

    6 outcome links · 9 safety-group records · 0 quality-of-life measures

    →

    NCT02062632 · Registry condition search · Scope: unclear

    Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy

    6 outcome links · 1 safety-group records · 3 quality-of-life measures

    →

    NCT02094261 · Source cited / selected · Scope: unclear

    Phase II AZD9291 Open Label Study in NSCLC After Previous EGFR TKI Therapy in EGFR and T790M Mutation Positive Tumours

    4 outcome links · 1 safety-group records · 0 quality-of-life measures

    →
    Source relationships and population-mapping limitations
    bindings
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice