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DISEASE & TREATMENT SETTING

LOQTORZI: metastatic Nasopharyngeal carcinoma (first-line)

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1.1 First-line Treatment of Metastatic or Recurrent, Locally Advanced NPC with Cisplatin and Gemcitabine LOQTORZI is indicated, in combination with cisplatin and gemcitabine, for the first-line treatment of adults with metastatic or with recurrent, locally advanced nasopharyngeal carcinoma (NPC).

Broader topic: Nasopharyngeal Carcinoma

Source population
Not part of this definition
Disease extent
metastatic
Treatment line
first-line
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for LOQTORZI (product label). Only dimensions stated in that wording are part of this definition.
      source wording
      1.1 First-line Treatment of Metastatic or Recurrent, Locally Advanced NPC with Cisplatin and Gemcitabine LOQTORZI is indicated, in combination with cisplatin and gemcitabine, for the first-line treatment of adults with metastatic or with recurrent, locally advanced nasopharyngeal carcinoma (NPC).

      Study evidence for this setting

      8 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00274937 · Registry condition search · Scope: unclear

      Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00492089 · Registry condition search · Scope: unclear

      Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

      1 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01256385 · Registry condition search · Scope: unclear

      Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01806675 · Registry condition search · Scope: unclear

      18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

      5 outcome links · 3 safety-group records · 1 quality-of-life measures

      →

      NCT02123511 · Registry condition search · Scope: unclear

      Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

      6 outcome links · 2 safety-group records · 3 quality-of-life measures

      →

      NCT02538510 · Registry condition search · Scope: unclear

      Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery

      4 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT03581786 · Source cited / selected · Scope: unclear

      The Efficacy and Safety Study of TORIPALIMAB INJECTION Combined With Chemotherapy for Nasophapyngeal Cancer

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT05070247 · Registry condition search · Scope: unclear

      A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

      6 outcome links · 14 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice