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DISEASE & TREATMENT SETTING

TIBSOVO: refractory Myelodysplastic Syndromes

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Relapsed or refractory Myelodysplastic Syndromes (MDS) For the treatment of adult patients with relapsed or refractory myelodysplastic syndromes ( 1.3 ).

Broader topic: Myelodysplastic Syndromes

Source population
Not part of this definition
Disease extent
refractory
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for TIBSOVO (product label). Only dimensions stated in that wording are part of this definition.
      source wording
      Relapsed or refractory Myelodysplastic Syndromes (MDS) For the treatment of adult patients with relapsed or refractory myelodysplastic syndromes ( 1.3 ).

      Study evidence for this setting

      53 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00040846 · Registry condition search · Scope: unclear

      Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

      5 outcome links · 6 safety-group records · 0 quality-of-life measures

      →

      NCT00049504 · Registry condition search · Scope: unclear

      Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer

      3 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00074490 · Registry condition search · Scope: unclear

      Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

      5 outcome links · 5 safety-group records · 0 quality-of-life measures

      →

      NCT00089011 · Registry condition search · Scope: unclear

      Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00096122 · Registry condition search · Scope: unclear

      Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00105001 · Registry condition search · Scope: unclear

      Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematolog

      5 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00118352 · Registry condition search · Scope: unclear

      Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00119366 · Registry condition search · Scope: unclear

      Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating P

      6 outcome links · 5 safety-group records · 0 quality-of-life measures

      →

      NCT00309842 · Registry condition search · Scope: unclear

      Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00354172 · Registry condition search · Scope: unclear

      Donor Umbilical Cord Blood Natural Killer Cells, Aldesleukin and Umbilical Cord Blood Transplant in Patients With Refractory Hematologic Cancers.

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00397813 · Registry condition search · Scope: unclear

      Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disor

      5 outcome links · 6 safety-group records · 0 quality-of-life measures

      →

      NCT00408681 · Registry condition search · Scope: unclear

      Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00462605 · Registry condition search · Scope: unclear

      MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia

      5 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00540995 · Registry condition search · Scope: unclear

      Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Myeloid Cancer

      1 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00589316 · Registry condition search · Scope: unclear

      Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myel

      6 outcome links · 8 safety-group records · 0 quality-of-life measures

      →

      NCT00719888 · Registry condition search · Scope: unclear

      Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00723099 · Registry condition search · Scope: unclear

      Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00789776 · Registry condition search · Scope: unclear

      Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolim

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT00795769 · Registry condition search · Scope: unclear

      Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00856388 · Registry condition search · Scope: unclear

      Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice