NCT03660826 · STUDY IN CONTEXT
Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following
Draft scope assessment: unclear. Attached because the study's own record describes recurrent disease. The study was not selected for this indication by its sponsor, and its eligibility has not been reconciled against this page in full. Found by searching ClinicalTrials.gov for this cancer type, restricted to studies that have posted results to the registry. No FDA notice, FDA label or NCI summary held by this site cites this study. Because the search asked for posted results, studies without posted results were never looked for, so their absence from this page means nothing.
Read the full study record and all posted results →
Linked outcomes
Mutations in Deoxyribonucleic Acid (DNA) Homologous Repair Genes
Will assess if markers of angiogenesis in serial plasma samples are associated with response to cediranib alone or in combination with olaparib.
Progression-free survival is defined as the time from the date of study enrollment to the investigator-determined date of progression or death due to any cause, whichever occurs first. For individuals who are alive and progression-free, the censored time at risk will be defined as the time from the study enrollment date to the date of the patient's last radiographic disease assessment.
Overall survival is defined as the time from the date of study enrollment to the date of death regardless of cause. For those individuals who have no death reported at the time of the analysis, the censored time at risk will be assessed from the date of study enrollment to the date that the patient was last contacted and known to be alive.
Objective tumor response was assessed in patients with measurable disease by the site investigator using RECIST v1.1. Patients with complete or partial tumor response were considered to have a response.
The number of patients who reported at least a grade 3 adverse event were assessed in those who initiated treatment.
Reported safety
Quality of life and patient-reported measures
No linked quality-of-life measure is recorded for this setting and study.
Full draft applicability and source-link record
- trial
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- trial label
- Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following
- applicability
- unclear
- applicability note
- Attached because the study's own record describes recurrent disease. The study was not selected for this indication by its sponsor, and its eligibility has not been reconciled against this page in full.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- provenance class
- registry-condition-search
- discovery note
- Found by searching ClinicalTrials.gov for this cancer type, restricted to studies that have posted results to the registry. No FDA notice, FDA label or NCI summary held by this site cites this study. Because the search asked for posted results, studies without posted results were never looked for, so their absence from this page means nothing.
- outcome Count
- 6
- harms Count
- 7
- qol Count
- 0
- outcomes
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0004
- source section id
- NCT03660826-om-0004
- source outcome index
- 4
- endpoint
- Mutations in Deoxyribonucleic Acid (DNA) Homologous Repair Genes
- endpoint definition
- Mutations in Deoxyribonucleic Acid (DNA) Homologous Repair Genes
- time origin
- Up to 5 years
- analysis role
- exploratory
- reporting status
- NOT_POSTED
- data cutoff
- Source null
- population note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0005
- source section id
- NCT03660826-om-0005
- source outcome index
- 5
- endpoint
- Markers of Angiogenesis in Serial Plasma Samples
- endpoint definition
- Will assess if markers of angiogenesis in serial plasma samples are associated with response to cediranib alone or in combination with olaparib.
- time origin
- Up to 5 years
- analysis role
- exploratory
- reporting status
- NOT_POSTED
- data cutoff
- Source null
- population note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- source section id
- NCT03660826-om-0000
- source outcome index
- 0
- endpoint
- Progression-free Survival
- endpoint definition
- Progression-free survival is defined as the time from the date of study enrollment to the investigator-determined date of progression or death due to any cause, whichever occurs first. For individuals who are alive and progression-free, the censored time at risk will be defined as the time from the study enrollment date to the date of the patient's last radiographic disease assessment.
- time origin
- Scans were done every 8 weeks for the first year and then every 12 weeks thereafter until disease progression. Vital status was assessed every 3 months for 2 years and then every 6 months for 3 years (5-years total).
- analysis role
- primary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- All patients randomized (Intent-to-Treat).
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0001
- source section id
- NCT03660826-om-0001
- source outcome index
- 1
- endpoint
- Overall Survival
- endpoint definition
- Overall survival is defined as the time from the date of study enrollment to the date of death regardless of cause. For those individuals who have no death reported at the time of the analysis, the censored time at risk will be assessed from the date of study enrollment to the date that the patient was last contacted and known to be alive.
- time origin
- Vital status was assessed every 3 months for 2 years and then every 6 months for 3 years (5-years total).
- analysis role
- secondary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- All patients randomized (Intent-to-Treat)
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0002
- source section id
- NCT03660826-om-0002
- source outcome index
- 2
- endpoint
- Objective Tumor Response
- endpoint definition
- Objective tumor response was assessed in patients with measurable disease by the site investigator using RECIST v1.1. Patients with complete or partial tumor response were considered to have a response.
- time origin
- Scans were done every 8 weeks for the first year; then every 12 weeks thereafter until disease progression is confirmed or up to 33 months.
- analysis role
- secondary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- All patients who are eligible for response assessment.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0003
- source section id
- NCT03660826-om-0003
- source outcome index
- 3
- endpoint
- Incidence of Adverse Events
- endpoint definition
- The number of patients who reported at least a grade 3 adverse event were assessed in those who initiated treatment.
- time origin
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy up to 50 months.
- analysis role
- secondary
- reporting status
- POSTED
- data cutoff
- Source null
- population note
- Patients who initiated assigned treatment.
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- arms
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- arm key
- OG000
- arm label
- Arm I (Cediranib maleate_Reference Group 1)
- regimen
- Patients randomized to Cedinarib reference arm during the recruitment period (09/04/2018-06/17/2019). Patients receive Cediranib maleate PO QD. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Cediranib: Given PO Cediranib Maleate: Given PO Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA
- analyzed count
- 40
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0000#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- arm key
- OG001
- arm label
- Arm II (Olaparib)
- regimen
- Patients receive olaparib PO BID. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 40
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0000#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- arm key
- OG002
- arm label
- Arm III (Cediranib Maleate, Olaparib)
- regimen
- Patients receive olaparib PO BID and cediranib maleate PO QD. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Cediranib: Given PO Cediranib Maleate: Given PO Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 40
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0000#groups/OG002
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- arm key
- OG003
- arm label
- Arm IV (Olaparib, Capivasertib)
- regimen
- Patients receive olaparib PO BID on days 1-28 and capivasertib PO BID on days 1-4 each week. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Capivasertib: Given PO Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 42
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0000#groups/OG003
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- arm key
- OG004
- arm label
- Arm V (Olaparib, Durvalumab)
- regimen
- Patients receive olaparib PO BID on days 1-28 and durvalumab IV on day 1. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Computed Tomography: Undergo CT scan Durvalumab: Given IV Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 42
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0000#groups/OG004
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- arm key
- OG005
- arm label
- Arm VI (Cediranib Maleate, Durvalumab)
- regimen
- Patients receive cediranib maleate PO QD on days 1-5 each week and durvalumab IV on day 1 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Cediranib Maleate: Given PO Computed Tomography: Undergo CT scan Durvalumab: Given IV Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA
- analyzed count
- 43
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0000#groups/OG005
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0000
- arm key
- OG006
- arm label
- Arm VII (Cediranib maleate_Reference Group 2)
- regimen
- Patients randomized to Cedinarib reference arm during the recruitment period (08/16/2021-06/28/2023). Patients receive cediranib maleate PO QD. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Cediranib: Given PO Cediranib Maleate: Given PO Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA
- analyzed count
- 41
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0000#groups/OG006
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0001
- arm key
- OG000
- arm label
- Arm I (Cediranib maleate_Referenc Group 1)
- regimen
- Patients randomized to Cedinarib reference arm during the recruitment period (09/04/2018-06/17/2019). Patients receive Cediranib maleate PO QD. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Cediranib: Given PO Cediranib Maleate: Given PO Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA
- analyzed count
- 40
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0001#groups/OG000
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0001
- arm key
- OG001
- arm label
- Arm II (Olaparib)
- regimen
- Patients receive olaparib PO BID. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 40
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0001#groups/OG001
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0001
- arm key
- OG002
- arm label
- Arm III (Cediranib Maleate, Olaparib)
- regimen
- Patients receive olaparib PO BID and cediranib maleate PO QD. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Cediranib: Given PO Cediranib Maleate: Given PO Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 40
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0001#groups/OG002
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0001
- arm key
- OG003
- arm label
- Arm IV (Olaparib, Capivasertib)
- regimen
- Patients receive olaparib PO BID on days 1-28 and capivasertib PO BID on days 1-4 each week. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Capivasertib: Given PO Computed Tomography: Undergo CT scan Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 42
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0001#groups/OG003
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- outcome key
- om-0001
- arm key
- OG004
- arm label
- Arm V (Olaparib, Durvalumab)
- regimen
- Patients receive olaparib PO BID on days 1-28 and durvalumab IV on day 1. Cycles repeat every 28 days in the absence of disease progression or unaccepted toxicity. Additionally, patients undergo blood sample collection, bone marrow aspiration and biopsy, CT, Echo or MUGA on study. Biospecimen Collection: Undergo blood sample collection Bone Marrow Aspirate: Undergo bone marrow aspiration and biopsy Bone Marrow Biopsy: Undergo bone marrow aspiration and biopsy Computed Tomography: Undergo CT scan Durvalumab: Given IV Echocardiography: Undergo Echo Multigated Acquisition Scan: Undergo MUGA Olaparib: Given PO
- analyzed count
- 42
- analyzed unit
- Participants
- is comparator
- Source null
- source pointer
- NCT03660826-om-0001#groups/OG004
- harms
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- harm key
- EG000
- source section id
- NCT03660826-ae
- event group key
- EG000
- event group label
- Arm I (Cediranib maleate_Reference Group 1)
- serious affected
- 17
- serious at risk
- 39
- other affected
- 38
- other at risk
- 39
- frequency threshold
- 0
- collection period
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy. Median follow-up was 22 months.
- event definition
- Patients randomized were included for the all-cause mortality summary. Patients randomized and also initiated treatment were included for the AE/SAE summary.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- harm key
- EG001
- source section id
- NCT03660826-ae
- event group key
- EG001
- event group label
- Arm II (Olaparib)
- serious affected
- 12
- serious at risk
- 40
- other affected
- 40
- other at risk
- 40
- frequency threshold
- 0
- collection period
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy. Median follow-up was 22 months.
- event definition
- Patients randomized were included for the all-cause mortality summary. Patients randomized and also initiated treatment were included for the AE/SAE summary.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- harm key
- EG002
- source section id
- NCT03660826-ae
- event group key
- EG002
- event group label
- Arm III (Cediranib Maleate, Olaparib)
- serious affected
- 19
- serious at risk
- 39
- other affected
- 39
- other at risk
- 39
- frequency threshold
- 0
- collection period
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy. Median follow-up was 22 months.
- event definition
- Patients randomized were included for the all-cause mortality summary. Patients randomized and also initiated treatment were included for the AE/SAE summary.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- harm key
- EG003
- source section id
- NCT03660826-ae
- event group key
- EG003
- event group label
- Arm IV (Olaparib, Capivasertib)
- serious affected
- 11
- serious at risk
- 42
- other affected
- 41
- other at risk
- 42
- frequency threshold
- 0
- collection period
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy. Median follow-up was 22 months.
- event definition
- Patients randomized were included for the all-cause mortality summary. Patients randomized and also initiated treatment were included for the AE/SAE summary.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- harm key
- EG004
- source section id
- NCT03660826-ae
- event group key
- EG004
- event group label
- Arm V (Olaparib, Durvalumab)
- serious affected
- 16
- serious at risk
- 42
- other affected
- 42
- other at risk
- 42
- frequency threshold
- 0
- collection period
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy. Median follow-up was 22 months.
- event definition
- Patients randomized were included for the all-cause mortality summary. Patients randomized and also initiated treatment were included for the AE/SAE summary.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- harm key
- EG005
- source section id
- NCT03660826-ae
- event group key
- EG005
- event group label
- Arm VI (Cediranib Maleate, Durvalumab)
- serious affected
- 13
- serious at risk
- 42
- other affected
- 40
- other at risk
- 42
- frequency threshold
- 0
- collection period
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy. Median follow-up was 22 months.
- event definition
- Patients randomized were included for the all-cause mortality summary. Patients randomized and also initiated treatment were included for the AE/SAE summary.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- release id
- clinical-indications-draft-1
- disease state id
- ds-endometrial-cancer-keytruda-qlex-1191efca
- nct id
- NCT03660826
- harm key
- EG006
- source section id
- NCT03660826-ae
- event group key
- EG006
- event group label
- Arm VII (Cediranib maleate_Reference Group 2)
- serious affected
- 19
- serious at risk
- 37
- other affected
- 37
- other at risk
- 37
- frequency threshold
- 0
- collection period
- Toxicity was assessed every other week for the first 8 weeks of study therapy and every 8 weeks after the completion or termination of study therapy. Median follow-up was 22 months.
- event definition
- Patients randomized were included for the all-cause mortality summary. Patients randomized and also initiated treatment were included for the AE/SAE summary.
- undenominated note
- Source null
- curation status
- draft
- reviewed by
- Source null
- reviewed at
- Source null
- created at
- 2026-09-10T00:00:00Z
- quality of life
- setting source links
Preserved source evidence · Not medical advice
Triangle