Phase II Trial Comparison of 3 vs 4 Fractions (BRACHY-FIT).

The film gives the main points. The full list below is copied from the registry; the study team makes the final decision.

• Age18 Years to no maximum
• SexAll
• Healthy volunteersNo

You may be able to join if

• Histologically documented malignancy of the cervix and planned to receive brachytherapy as part of definitive treatment.
• ECOG performance status of 0-2
• Age ≥ 18 years old.
• Ability to understand and the willingness to provide written informed consent.

You cannot join if

• Contraindication to receiving radiotherapy as determined by treating radiation oncologist.
• Contraindication to receiving MRI.
• Prior radiation to the pelvis > 3 months ago
• Age < 18 years old.
• Pregnant or breast-feeding

This is how the treatment is meant to work. Whether it helps, and how safe it is, is what this trial is testing.

Treatments listed in the registry

• 3-Fraction HDR Brachytherapy (Radiation): 8 Gy per fraction for 3 fractions (total 24 Gy) for patients with locally advanced cervical cancer, based on individualized planning.
• 4-Fraction HDR Brachytherapy (Radiation): 7 Gy per fraction for 4 fractions (total 28 Gy) as the standard-of-care brachytherapy regimen.

Non Randomized · Parallel · masking: None

Main goals

• Proportion of Patients Receiving 3-Fraction Brachytherapy Regimen (Up to 8 months)

Planned enrollment: 41 (estimated).

• Stanford University, Palo Alto, California

Site status as of Oct 30, 2026. Check the live record before contacting a site.

• ClinicalTrials.gov NCT07022470

Registry record reviewed as fetched Oct 30, 2026, last updated by the sponsor Jun 11, 2026. Public record; not medical advice.