5-Day Preoperative Radiation for Soft Tissue Sarcoma

The film gives the main points. The full list below is copied from the registry; the study team makes the final decision.

• Age18 Years to no maximum
• SexAll
• Healthy volunteersNo

You may be able to join if

• Histologically confirmed soft tissue sarcoma of the extremity, trunk or retroperitoneum.
• Has been offered preoperative radiation and surgery as part of standard-of-care treatment
• Age ≥ 18
• KPS ≥ 70 or ECOG 0 to 2
• Life expectancy ≥ 6 months
• If a woman is of childbearing potential, a negative serum or urine pregnancy test must be documented.
• Ability to understand and the willingness to personally sign the written IRB approved informed consent document.

You cannot join if

• History of prior radiation to the area to be treated.
• Active use of other anti-cancer investigational agents.
• Planned use of concurrent chemotherapy, targeted therapy, or immunotherapy with radiation therapy (defined as the time interval starting 1 week before the first and last fraction of radiation therapy and surgery).
• Pregnancy.

This is how the treatment is meant to work. Whether it helps, and how safe it is, is what this trial is testing.

Treatments listed in the registry

• External Beam Radiotherapy (Radiation): Radiation will be delivered by external beam techniques to the tumor and areas of possible microscopic disease at a dose of 30 Gy divided into 5 equal fractions of 6 Gy (administered over a total of 5 to 10 business day

Na · Single Group · masking: None

As the registry describes them. Requirements to join, such as a tissue sample, are in the eligibility list above even when on-study procedures are optional. Ask the study team which steps apply to you.

• radiation: Part of the study plan

Main goals

• Post-operative Complication Rate (120 days after surgery)

Other goals

• Local Recurrence Rate

Planned enrollment: 75 (estimated).

• Stanford University, Palo Alto, California

Site status as of Oct 30, 2026. Check the live record before contacting a site.

• ClinicalTrials.gov NCT06087861

Registry record reviewed as fetched Oct 30, 2026, last updated by the sponsor Jun 9, 2026. Public record; not medical advice.