Treatment of Cystic Partially Differentiated Nephroblastoma

Source: Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 15, 2025 · Captured 2026-09-09.

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Surgery is the main treatment. Preoperative chemotherapy administration was reported in 20 of 98 patients. None of the preoperatively treated patients showed response to chemotherapy on imaging or histological examination.[1]

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Standard treatment options for cystic partially differentiated nephroblastoma include the following:

Surgery. Patients with stage I disease have a 100% survival rate with surgery alone.[4]

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Surgery and adjuvant chemotherapy. Patients with stage II disease have an excellent outcome with tumor resection followed by postoperative vincristine and dactinomycin.[4]

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Preserved source evidence · Not medical advice