Radical nephrectomy with lymph node sampling

Source: Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 15, 2025 · Captured 2026-09-09.

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Context: Renal Cell Carcinoma (RCC) / Treatment of RCC

The primary treatment for RCC includes total surgical removal of the kidney and associated lymph nodes.[34]

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Pediatric patients with translocation-positive RCC often have a better outcome than adult patients, which is generally attributed to a smaller percentage of distant metastasis in pediatric patients.[41] In younger patients, the disease is often managed with surgery alone. Of three pediatric patients (aged 3–12 years) in one study, two had previously received chemotherapy to treat retinoblastoma and neuroblastoma. All three patients underwent surgery only and remained disease free. These patients had a lower copy-number burden than the adults in the series.[37][Level of evidence C1]

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Preserved source evidence · Not medical advice