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Stage V Wilms tumor and children at high risk of developing bilateral Wilms tumor
Source: Wilms Tumor (PDQ®)–Patient Version, National Cancer Institute.
Source updated: May 12, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Context: Treatment of Wilms tumor by stage and histology
Treatment of stage V Wilms tumor or bilateral Wilms tumor may be different for each child and may include:
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Combination chemotherapy to shrink the tumor, followed by repeat imaging at 6 to 12 weeks to decide on further treatment. A biopsy may be done or treatment may be given, including partial nephrectomy, continued chemotherapy, or radiation therapy.
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A biopsy of the kidneys, followed by combination chemotherapy to shrink the tumor. Then, surgery is done to remove as much of the cancer as possible. If cancer remains after surgery, your child may have chemotherapy and possibly radiation therapy.
If a kidney transplant is needed because of kidney problems, it is usually delayed until 1 to 2 years after treatment is completed and there are no signs of cancer.
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice