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Stage IV Wilms tumor
Source: Wilms Tumor (PDQ®)–Patient Version, National Cancer Institute.
Source updated: May 12, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Context: Treatment of Wilms tumor by stage and histology
Treatment of stage IV Wilms tumor with favorable histology may include:
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Nephrectomy with removal of lymph nodes, followed by combination chemotherapy. Radiation therapy may be given to the area where the tumor was or to other parts of the abdomen.
Radiation therapy to treat cancer that has spread to other parts of the body.
Treatment of stage IV anaplastic Wilms tumor may include:
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nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen and combination chemotherapy
chemotherapy given before nephrectomy with removal of lymph nodes, followed by radiation therapy to the abdomen
radiation therapy to treat cancer that has spread to other parts of the body
Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice