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Treatment Options for Recurrent Vulvar Cancer
Source: Vulvar Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 14, 2025 · Captured 2026-09-09.
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Context: Treatment of Recurrent Vulvar Cancer
Treatment options for recurrent vulvar cancer include:
Wide local excision with or without radiation therapy in patients with local recurrence.
Radical vulvectomy and pelvic exenteration in patients with local recurrence.
Synchronous radiation therapy and cytotoxic chemotherapy with or without surgery.[1]
Source links and citations
Treatment and outcome depend on the site and extent of recurrence.[2] Radical excision of localized recurrence may be considered if technically feasible.[3] Palliative radiation therapy is used for some patients. Radiation therapy with or without chemotherapy may be associated with substantial disease-free periods in some patients with a small local recurrence.[1,4,5] When local recurrence occurs more than 2 years after primary treatment, a combination of radiation therapy and surgery may result in a 5-year survival rate of greater than 50%.[6,7]
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Preserved source evidence · Not medical advice