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← Vaginal Cancer

FOR PATIENTS · SOURCE READING

Treatment of Stage II, Stage III, and Stage IVA Vaginal Cancer

Source: Vaginal Cancer Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: April 5, 2023 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

For information about the treatments listed below, see the Treatment Option Overview section.

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Treatment of stage II, stage III, and stage IVA vaginal cancer is the same for squamous cell cancer and adenocarcinoma. Treatment may include the following:

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Internal and/or external radiation therapy to the vagina. Radiation therapy may also be given to the lymph nodes near tumors in the lower part of the vagina.

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Surgery (vaginectomy or pelvic exenteration) with or without radiation therapy.

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Chemotherapy given with radiation therapy.

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Preserved source evidence · Independent clinical review pending · Not medical advice