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Treatment Options for Stage II Uterine Sarcoma
Source: Uterine Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: December 17, 2024 · Captured 2026-09-09.
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Context: Treatment of Stage II Uterine Sarcoma
Treatment options for stage II uterine sarcoma include:
Surgery (total abdominal hysterectomy, bilateral salpingo-oophorectomy, and pelvic and periaortic selective lymphadenectomy).
Surgery plus pelvic radiation therapy.
Surgery plus adjuvant chemotherapy.
Surgery plus adjuvant radiation therapy.
A nonrandomized Gynecologic Oncology Group study examined the effect of pelvic radiation therapy on patients with stage I and II carcinosarcomas. Patients who had pelvic radiation therapy had a significant reduction in tumor recurrences within the radiation treatment field but no alteration in survival.[1] One nonrandomized study that predominantly included patients with carcinosarcomas showed that adjuvant chemotherapy with cisplatin and doxorubicin benefitted participants.[2]
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