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← Cancer of Unknown Primary (CUP)

FOR PATIENTS · SOURCE READING

Key Points

Source: Carcinoma of Unknown Primary Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: December 17, 2021 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Treatment Option Overview

There are different types of treatment for patients with carcinoma of unknown primary (CUP).

Four types of standard treatment are used:

Four types of standard treatment are used:

Surgery

Four types of standard treatment are used:

Radiation therapy

Four types of standard treatment are used:

Chemotherapy

Four types of standard treatment are used:

Hormone therapy

New types of treatment are being tested in clinical trials.

Treatment for carcinoma of unknown primary may cause side effects.

Patients may want to think about taking part in a clinical trial.

Patients can enter clinical trials before, during, or after starting their cancer treatment.

Preserved source evidence · Independent clinical review pending · Not medical advice