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Treatment of stage III testicular cancer
Source: Testicular Cancer Treatment by Stage, National Cancer Institute.
Source updated: May 17, 2023 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
NCI patient treatment article for this disease Exact source article; not a clinically reviewed indication or current-standard recommendation.
Context: Testicular Cancer Treatment by Stage
Treatment of stage III testicular cancer
Treatment of stage III testicular cancer depends on whether the cancer is a seminoma or a nonseminoma.
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Treatment of seminoma may include the following:
Surgery to remove the testicle, followed by combination chemotherapy. If there are tumors remaining after chemotherapy, treatment may be one of the following:
Surgery to remove the testicle, followed by combination chemotherapy. If there are tumors remaining after chemotherapy, treatment may be one of the following:
Surveillance with no treatment unless tumors grow.
Surgery to remove the testicle, followed by combination chemotherapy. If there are tumors remaining after chemotherapy, treatment may be one of the following:
Surveillance for tumors smaller than 3 centimeters and surgery to remove tumors larger than 3 centimeters.
Surgery to remove the testicle, followed by combination chemotherapy. If there are tumors remaining after chemotherapy, treatment may be one of the following:
A PET scan two months after chemotherapy and surgery to remove tumors that show up with cancer on the scan.
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A clinical trial of chemotherapy.
Treatment of nonseminoma may include the following:
Surgery to remove the testicle, followed by combination chemotherapy.
Combination chemotherapy followed by surgery to remove the testicle and all remaining tumors. Additional chemotherapy may be given if the tumor tissue removed contains cancer cells that are growing or if follow-up tests show that cancer is progressing.
Combination chemotherapy before surgery to remove the testicle, for cancer that has spread and is thought to be life-threatening.
A clinical trial of chemotherapy.
Preserved source evidence · Independent clinical review pending · Not medical advice