HEALTH PROFESSIONAL · SOURCE READING
Poor Prognosis
Source: Testicular Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 16, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Context: Treatment Option Overview for Testicular Cancer
Nonseminoma:
Mediastinal primary, or
Nonpulmonary visceral metastases, or
For markers–any of:
For markers–any of:
AFP more than 10,000 ng/mL, or
For markers–any of:
Beta-hCG more than 50,000 IU/mL (10,000 ng/mL), or
For markers–any of:
LDH more than 10 × the upper limit of normal
A total of 16% to 26% of nonseminomas are poor prognosis. The 5-year PFS rate is 41%; the 5-year survival rate is 71%.
Seminoma:
No patients are classified as poor prognosis.
Preserved source evidence · Not medical advice
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