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← Small Intestine Cancer

HEALTH PROFESSIONAL · SOURCE READING

Treatment of Recurrent Small Intestine Cancer

Source: Small Intestine Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: March 6, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Treatment options:

For metastatic adenocarcinoma or leiomyosarcoma:

For metastatic adenocarcinoma or leiomyosarcoma:

No standard effective chemotherapy exists for patients with recurrent metastatic adenocarcinoma or leiomyosarcoma of the small intestine. These patients should consider enrolling in phase I or II clinical trials evaluating new anticancer drugs or biological therapy.

For locally recurrent disease:

For locally recurrent disease:

Surgery.

For locally recurrent disease:

Palliative radiation therapy.

For locally recurrent disease:

Palliative chemotherapy.

For locally recurrent disease:

Clinical trials evaluating ways of improving local control, such as the use of radiation therapy with radiosensitizers with or without systemic chemotherapy.

Preserved source evidence · Not medical advice