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Treatment Options for High-Grade Stage I Major Salivary Gland Tumors
Source: Salivary Gland Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 13, 2025 · Captured 2026-09-09.
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Context: Treatment of Stage I Major Salivary Gland Cancer
Treatment options for high-grade stage I major salivary gland tumors include:
Localized high-grade salivary gland tumors that are confined to the gland in which they arise may be cured by radical surgery alone.
Postoperative radiation therapy may improve local control and increase survival rates for patients with high-grade tumors, positive surgical margins, or perineural invasion.[8][Level of evidence C2]; [9-11]
Source links and citations
Clinical trials exploring newer methods of local control are appropriate.
High-grade stage I salivary gland tumors that are confined to the gland in which they arise may be cured by surgery alone. Adjuvant radiation therapy may be used, especially with the presence of positive margins.
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Preserved source evidence · Not medical advice