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Endocrine Therapy
Source: Breast Cancer Treatment During Pregnancy (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: December 4, 2024 · Captured 2026-09-09.
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Context: Treatment of Early/Localized/Operable Breast Cancer During Pregnancy
Endocrine therapy is generally avoided until after delivery. Case reports and a literature review of tamoxifen during pregnancy show that tamoxifen administration during pregnancy is associated with vaginal bleeding, miscarriage, congenital abnormalities such as Goldenhar syndrome, and fetal death.[19-21] Breastfeeding is also not recommended concurrently with endocrine therapy.[22]
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