TriangleHEALTH PROFESSIONAL · SOURCE READING
Nasal Vestibule Tumors
Source: Paranasal Sinus and Nasal Cavity Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: July 5, 2024 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Context: Treatment of Stage IV Paranasal Sinus and Nasal Cavity Cancer
Treatment options for stage IV nasal vestibule tumors include the following:
Generally, radiation therapy is preferred to minimize deformity. External-beam (i.e., photons or electrons) and/or interstitial implantation can be used. Surgery is reserved for salvage. Treatment of the neck should be considered.
Clinical trials for advanced tumors should be considered to evaluate chemotherapy preoperatively or before radiation therapy. Adjuvant therapy after surgery or after combined-modality therapy should also be considered.
Concurrent chemotherapy and radiation therapy may be considered.
Neoadjuvant chemotherapy as used in clinical trials has been used to shrink tumors and to render them more definitively treatable with either surgery or radiation therapy. This chemotherapy is given before the other modalities; therefore, the designation of neoadjuvant is used to distinguish it from standard adjuvant therapy, which is given after or during definitive therapy with radiation or after surgery. Many drug combinations have been used in neoadjuvant chemotherapy.[6-8]
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Preserved source evidence · Not medical advice