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← Pancreatic Cancer

FOR PATIENTS · SOURCE READING

Treatment of Resectable or Borderline Resectable Pancreatic Cancer

Source: Pancreatic Cancer Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: July 8, 2026 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Treatment of resectable or borderline resectable pancreatic cancer may include:

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chemotherapy with or without radiation therapy, followed by surgery

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surgery

surgery, followed by chemotherapy

surgery, followed by chemoradiation

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a clinical trial of chemotherapy and/or radiation therapy before surgery

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a clinical trial of chemoradiation, followed by surgery and then chemotherapy

a clinical trial of different ways of giving radiation therapy

Surgery to remove the tumor may include Whipple procedure, total pancreatectomy, or distal pancreatectomy.

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Palliative therapy can be started at any stage of disease. Visit the Palliative Therapy section for information about treatments that may improve quality of life or relieve symptoms in people with pancreatic cancer.

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Learn more about these treatments in the Treatment Option Overview.

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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

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Preserved source evidence · Independent clinical review pending · Not medical advice