HEALTH PROFESSIONAL · SOURCE READING
Treatment Option Overview for Ovarian Germ Cell Tumors
Source: Ovarian Germ Cell Tumors Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: September 18, 2024 · Captured 2026-09-09.
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Treatment options for patients with ovarian germ cell tumors include:
Surgery.
Chemotherapy.
Radiation therapy.
High-dose chemotherapy with bone marrow transplant (under clinical evaluation).
Patients may be treated with unilateral salpingo-oophorectomy or total abdominal hysterectomy and bilateral salpingo-oophorectomy.
All patients except those with stage I, grade I immature teratoma and stage IA dysgerminoma require postoperative chemotherapy. With platinum-based combination chemotherapy, the prognosis for patients with endodermal sinus tumors, immature teratomas, embryonal carcinomas, choriocarcinomas, and mixed tumors containing one or more of these elements has improved dramatically.[1] As new and more effective drugs are developed, many of these patients will be candidates for newer clinical trials.
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