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Treatment of Stage IV Ovarian Germ Cell Tumors
Source: Ovarian Germ Cell Tumors Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: March 31, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
For information about the treatments listed below, see the Treatment Option Overview section.
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Treatment depends on whether the tumor is a dysgerminoma or another type of ovarian germ cell tumor.
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Treatment of dysgerminoma may include:
Total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by chemotherapy, with removal of as much of the cancer in the pelvis and abdomen as possible.
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Unilateral salpingo-oophorectomy followed by chemotherapy.
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Treatment of other ovarian germ cell tumors may include:
Total abdominal hysterectomy and bilateral salpingo-oophorectomy, with removal of as much of the cancer in the pelvis and abdomen as possible. Chemotherapy will be given before and/or after surgery.
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Unilateral salpingo-oophorectomy followed by chemotherapy.
Second-look laparotomy (surgery done after primary treatment to see if tumor cells remain).
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A clinical trial of a new treatment.
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice