FOR PATIENTS · SOURCE READING
Chemotherapy
Source: Osteosarcoma Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: February 25, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Context: Treatment Option Overview / The following types of treatment are used:
Chemotherapy (also called chemo) uses drugs to stop the growth of cancer cells. Chemotherapy either kills the cancer cells or stops them from dividing. Chemotherapy may be given alone or with other types of treatment.
Chemotherapy for osteosarcoma and UPS is injected into a vein. When given this way, the drugs enter the bloodstream and can reach cancer cells throughout the body. Chemotherapy is usually given before and after surgery to remove the tumor.
Source links and citations
Chemotherapy drugs used alone or in combination to treat osteosarcoma include:
carboplatin
Source links and citations
cisplatin
Source links and citations
cyclophosphamide
Source links and citations
docetaxel
Source links and citations
doxorubicin
Source links and citations
etoposide
Source links and citations
gemcitabine
Source links and citations
ifosfamide
Source links and citations
methotrexate
Source links and citations
Other chemotherapy drugs not listed here may also be used.
Learn more about how chemotherapy works, how it is given, common side effects, and more at Chemotherapy to Treat Cancer.
Source links and citations
Preserved source evidence · Independent clinical review pending · Not medical advice
Triangle