FOR PATIENTS · SOURCE READING
Treatment of Localized Osteosarcoma and Undifferentiated Pleomorphic Sarcoma (UPS) of Bone
Source: Osteosarcoma Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: February 25, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
Treatment of newly diagnosed localized osteosarcoma and UPS of bone may include:
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surgery to remove the tumor
chemotherapy before or after surgery to remove the tumor
radiation therapy if surgery cannot be done or if the tumor was not completely removed by surgery
Learn about these treatments in the Treatment Option Overview.
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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.
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Preserved source evidence · Independent clinical review pending · Not medical advice
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