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HEALTH PROFESSIONAL · SOURCE READING

Endobronchial therapies

Source: Non-Small Cell Lung Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 15, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Stage 0 NSCLC / Treatment Options for Stage 0 NSCLC

Patients with central lesions may be candidates for curative endobronchial therapy. Endobronchial therapies that preserve lung function include photodynamic therapy, electrocautery, cryotherapy, and Nd-YAG laser therapy.[3-6]

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Evidence (endobronchial therapies):

Small case series have reported high complete response rates and long-term survival in selected patients.[7,8][Level of evidence C2]

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Efficacy of these treatment modalities in the management of patients with early NSCLC remains to be proven in definitive randomized controlled trials.

A high incidence of second primary cancers develop in these patients.[1,2]

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Publication references

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Preserved source evidence · Not medical advice