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Treatment of neuroblastoma is based on risk groups.
Source: Neuroblastoma Treatment (PDQ®)–Patient Version, National Cancer Institute.
Source updated: October 23, 2024 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.
For many types of cancer, stages are used to plan treatment. For neuroblastoma, treatment depends on the patient's risk group. The risk group is determined by the following factors:
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the stage of the cancer
the child's age at diagnosis
the International Neuroblastoma Pathologic Classification (INPC) (tumor histology)
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whether the tumors are diploid or hyperdiploid (DNA index)
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whether the cancer gene MYCN is found in the tumor cells
how much of the cancer could be removed by surgery
There are three risk groups: low risk, intermediate risk, and high risk.
Low-risk and intermediate-risk neuroblastoma have a good chance of being cured.
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High-risk neuroblastoma may be hard to cure.
For more information on the risk group classification, see the Revised International Neuroblastoma Response Criteria (INRC) section in Neuroblastoma Treatment (Health Professional Version).
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Preserved source evidence · Independent clinical review pending · Not medical advice