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Surgery followed by observation
Source: Neuroblastoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: April 28, 2025 · Captured 2026-09-09.
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Treatment for patients categorized as low risk may be surgery alone. For more information, see Table 3.
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Evidence (surgery followed by observation):
Results from the COG-P9641 (NCT00003119) study showed that surgery alone, even without complete resection, can cure nearly all patients with stage 1 neuroblastoma and the vast majority of patients with asymptomatic, favorable-biology, and International Neuroblastoma Staging System (INSS) stage 2A or stage 2B disease.[3]
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Similar outcomes were seen in a nonrandomized clinical trial in Japan.[6]
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Preserved source evidence · Not medical advice