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← Myeloproliferative Neoplasms

HEALTH PROFESSIONAL · SOURCE READING

Treatment Option Overview for CNL

Source: Myeloproliferative Neoplasms Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: September 27, 2024 · Captured 2026-09-09.

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Context: Treatment of Chronic Neutrophilic Leukemia

In the past, the treatment of CNL focused on disease control rather than cure. Once the disease progressed to a more aggressive leukemia, there was typically little chance of obtaining a long-lasting remission because of the older age of most patients, as well as the acquisition of multiple poor prognostic cytogenetic abnormalities. Allogeneic bone marrow transplant represents a potentially curative treatment modality for CNL.[6-8] Results vary with the use of traditional chemotherapies including hydroxyurea and interferon.[9]

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