Treatment Option Overview for Plasma Cell Neoplasms

Source: Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 25, 2025 · Captured 2026-09-09.

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The major challenge in treating plasma cell neoplasms is separating the stable asymptomatic patients who do not require immediate treatment from patients with progressive symptomatic myeloma who may need to be treated immediately.[1-3] Monoclonal gammopathy of undetermined significance or smoldering myeloma must be distinguished from progressive myeloma.

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Asymptomatic Plasma Cell Neoplasms (Smoldering Multiple Myeloma) →Symptomatic Plasma Cell Neoplasms →

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