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Chemotherapy
Source: Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: April 25, 2025 · Captured 2026-09-09.
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Context: Treatment of Isolated Plasmacytoma of Bone / Treatment Options for Isolated Plasmacytoma of Bone
Most patients eventually develop disseminated disease and require chemotherapy. Almost 50% of patients do so within 2 years of diagnosis.[2,3] However, patients with serum paraprotein or Bence Jones protein, who have complete disappearance of these proteins after radiation therapy, may remain free of disease for prolonged periods.[2,4] Patients with a negative flow cytometry on bone marrow examination for plasma cell infiltration are also unlikely to relapse.[5] Patients with progression to multiple myeloma often have good responses to chemotherapy, with a median survival of 63 months after progression.[2,4]
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