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← Plasma Cell Neoplasms (Including Multiple Myeloma)

FOR PATIENTS · SOURCE READING

Treatment of Monoclonal Gammopathy of Undetermined Significance

Source: Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: November 17, 2023 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

For information about the treatments listed below, see the Treatment Option Overview section.

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Treatment of monoclonal gammopathy of undetermined significance (MGUS) is usually watchful waiting. Regular blood tests to check the level of M protein in the blood and physical exams to check for signs or symptoms of cancer will be done.

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Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

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Preserved source evidence · Independent clinical review pending · Not medical advice