High-dose chemotherapy and radiation therapy with stem cell transplant

Source: Mycosis Fungoides (Including Sézary Syndrome) Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: February 12, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

NCI-linked patient version: mycosis fungoides and Sezary syndrome subset Patient source covers mycosis fungoides/Sezary syndrome; do not apply to all other cutaneous T-cell lymphomas.

Context: Treatment Option Overview / Seven types of standard treatment are used:

High doses of chemotherapy and sometimes radiation therapy are given to kill cancer cells. Healthy cells, including blood-forming cells, are also destroyed by the cancer treatment. Stem cell transplant is a treatment to replace the blood-forming cells. Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored. After the patient completes chemotherapy and radiation therapy, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the body's blood cells.

Source links and citations

Preserved source evidence · Independent clinical review pending · Not medical advice