Treatment Option Overview for Mycosis Fungoides and Other Cutaneous T-Cell Lymphomas

Anecdotal responses, some lasting for months, can be seen with aggressive antibiotic treatment of Staphylococcus aureus, with corresponding decreased expression of interleukin-2 receptors, STAT signaling, and T-cell proliferation.[1][Level of evidence C3]

These types of treatments produce remissions, but long-term remissions are uncommon. Treatment is considered palliative for most patients, although major symptomatic improvement is regularly achieved. Survival of more than 8 years is common for patients with early stages of disease. All patients with cutaneous T-cell lymphomas are candidates for clinical trials evaluating new approaches to treatment.