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← Malignant Mesothelioma

HEALTH PROFESSIONAL · SOURCE READING

Pemetrexed

Source: Malignant Mesothelioma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: May 12, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Recurrent Malignant Mesothelioma / Treatment Options for Recurrent Malignant Mesothelioma

Evidence (pemetrexed):

A large randomized study compared pemetrexed with best supportive care in 243 patients who received one previous regimen of chemotherapy that did not include pemetrexed.[11][Level of evidence A1]

Source links and citations

A large randomized study compared pemetrexed with best supportive care in 243 patients who received one previous regimen of chemotherapy that did not include pemetrexed.[11][Level of evidence A1]

No survival benefit was shown in patients who received pemetrexed, although the PFS rate, time-to-progression, and the response rates favored the pemetrexed arm.

Publication references

Read the original reference and check its publication notices.

Preserved source evidence · Not medical advice