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Systematic Treatment for Unresectable Stage III, Stage IV, and Recurrent Disease
Source: Melanoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.
Source updated: May 2, 2025 · Captured 2026-09-09.
Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.
Context: Treatment Option Overview for Melanoma
Treatment options for patients with metastatic melanoma have rapidly expanded over the last decade. Two approaches—checkpoint inhibition and targeting the mitogen-activated protein kinase pathway—have improved OS in randomized trials. Given the rapid development of new agents and combinations, patients may consider a clinical trial for initial treatment and at the time of any subsequent progression.
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Preserved source evidence · Not medical advice