HEALTH PROFESSIONAL · SOURCE READING

Treatment Option Overview for Male Breast Cancer

Source: Male Breast Cancer Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: February 28, 2025 · Captured 2026-09-09.

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The approach to the treatment of men with breast cancer is similar to that for women. Because male breast cancer is rare, there is a lack of randomized data to support specific treatment modalities. Treatment options for men with breast cancer are described in Table 1.

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Table 1

Table 1. Treatment Options for Male Breast Cancer
Stage (TNM Definitions)	Treatment Options
T = primary tumor; N = regional lymph node; M = distant metastasis; GnRH = gonadotropin-releasing hormone.
Early/localized/operable male breast cancer	Surgery with or without radiation therapy
Early/localized/operable male breast cancer	Adjuvant therapy
Locally advanced male breast cancer	Neoadjuvant chemotherapy
	Surgical excision
	Radiation therapy and endocrine therapy
Metastatic male breast cancer	Aromatase inhibitor therapy in conjunction with a GnRH agonist

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Preserved source evidence · Not medical advice